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Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm

BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. METHODS: Patients with early gastric tumors who were treated by ESD f...

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Autores principales: Lee, Hyun Jik, Lee, Yoo Jin, Lee, Ju Yup, Kim, Eun Soo, Chung, Woo Jin, Jang, Byoung Kuk, Park, Kyung Sik, Hwang, Jae Seok, Cho, Kwang Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Gastrointestinal Endoscopy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997068/
https://www.ncbi.nlm.nih.gov/pubmed/29621878
http://dx.doi.org/10.5946/ce.2017.109
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author Lee, Hyun Jik
Lee, Yoo Jin
Lee, Ju Yup
Kim, Eun Soo
Chung, Woo Jin
Jang, Byoung Kuk
Park, Kyung Sik
Hwang, Jae Seok
Cho, Kwang Bum
author_facet Lee, Hyun Jik
Lee, Yoo Jin
Lee, Ju Yup
Kim, Eun Soo
Chung, Woo Jin
Jang, Byoung Kuk
Park, Kyung Sik
Hwang, Jae Seok
Cho, Kwang Bum
author_sort Lee, Hyun Jik
collection PubMed
description BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. METHODS: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed. RESULTS: In total, 643 patients were included. The mean duration of endoscopic follow-up was 45.27±27.59 (range, 12–148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions. CONCLUSIONS: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm.
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spelling pubmed-59970682018-06-19 Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm Lee, Hyun Jik Lee, Yoo Jin Lee, Ju Yup Kim, Eun Soo Chung, Woo Jin Jang, Byoung Kuk Park, Kyung Sik Hwang, Jae Seok Cho, Kwang Bum Clin Endosc Original Article BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. METHODS: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed. RESULTS: In total, 643 patients were included. The mean duration of endoscopic follow-up was 45.27±27.59 (range, 12–148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions. CONCLUSIONS: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm. Korean Society of Gastrointestinal Endoscopy 2018-05 2018-04-06 /pmc/articles/PMC5997068/ /pubmed/29621878 http://dx.doi.org/10.5946/ce.2017.109 Text en Copyright © 2018 Korean Society of Gastrointestinal Endoscopy This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Hyun Jik
Lee, Yoo Jin
Lee, Ju Yup
Kim, Eun Soo
Chung, Woo Jin
Jang, Byoung Kuk
Park, Kyung Sik
Hwang, Jae Seok
Cho, Kwang Bum
Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title_full Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title_fullStr Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title_full_unstemmed Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title_short Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
title_sort characteristics of synchronous and metachronous multiple gastric tumors after endoscopic submucosal dissection of early gastric neoplasm
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997068/
https://www.ncbi.nlm.nih.gov/pubmed/29621878
http://dx.doi.org/10.5946/ce.2017.109
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