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Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends

The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvant...

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Detalles Bibliográficos
Autores principales:	Sohail, Muhammad Farhan, Rehman, Mubashar, Sarwar, Hafiz Shoaib, Naveed, Sara, Salman, Omer, Bukhari, Nadeem Irfan, Hussain, Irshad, Webster, Thomas J, Shahnaz, Gul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997133/ https://www.ncbi.nlm.nih.gov/pubmed/29922053 http://dx.doi.org/10.2147/IJN.S164518

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