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A new method for predicting essential proteins based on participation degree in protein complex and subgraph density

Essential proteins are crucial to living cells. Identification of essential proteins from protein-protein interaction (PPI) networks can be applied to pathway analysis and function prediction, furthermore, it can contribute to disease diagnosis and drug design. There have been some experimental and...

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Detalles Bibliográficos
Autores principales: Lei, Xiujuan, Yang, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997351/
https://www.ncbi.nlm.nih.gov/pubmed/29894517
http://dx.doi.org/10.1371/journal.pone.0198998