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Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat

Circadian clocks, present in almost all cells of the body, are entrained to rhythmic changes in the environment (e.g. light/dark cycles). Genes responsible for this timekeeping are named core-clock genes, which through transcriptional feedback interactions mediated by transcription factor binding to...

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Detalles Bibliográficos
Autores principales: Mavroudis, Panteleimon D., DuBois, Debra C., Almon, Richard R., Jusko, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997360/
https://www.ncbi.nlm.nih.gov/pubmed/29894471
http://dx.doi.org/10.1371/journal.pone.0197534