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Continuous-Flow In-Line Solvent-Swap Crystallization of Vitamin D(3)
[Image: see text] A continuous tandem in-line evaporation–crystallization is presented. The process includes an in-line solvent-swap step, suitable to be coupled to a capillary based cooler. As a proof of concept, this setup is tested in a direct in-line acetonitrile mediated crystallization of Vita...
Autores principales: | Escribà-Gelonch, Marc, Hessel, Volker, Maier, Manuel C., Noël, Timothy, Neira d’Angelo, Maria Fernanda, Gruber-Woelfler, Heidrun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997464/ https://www.ncbi.nlm.nih.gov/pubmed/29910596 http://dx.doi.org/10.1021/acs.oprd.7b00351 |
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