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A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies
CAR T-cell therapies hold great promise for treating a range of malignancies but are however challenged by the complexity of their production and by the adverse events related to their activity. Here we report the development of the CubiCAR, a tri-functional CAR architecture that enables CAR T-cell...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997667/ https://www.ncbi.nlm.nih.gov/pubmed/29895885 http://dx.doi.org/10.1038/s41598-018-27264-w |