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The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells
Extracellular ATP is an important short-range signaling molecule that promotes various physiological responses virtually in all cell types, including pancreatic β-cells. It is well documented that pancreatic β-cells release ATP through exocytosis of insulin granules upon glucose stimulation. We hypo...
Autores principales: | Tozzi, Marco, Larsen, Anna T., Lange, Sofie C., Giannuzzo, Andrea, Andersen, Martin N., Novak, Ivana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997690/ https://www.ncbi.nlm.nih.gov/pubmed/29895988 http://dx.doi.org/10.1038/s41598-018-27281-9 |
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