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The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells

Extracellular ATP is an important short-range signaling molecule that promotes various physiological responses virtually in all cell types, including pancreatic β-cells. It is well documented that pancreatic β-cells release ATP through exocytosis of insulin granules upon glucose stimulation. We hypo...

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Detalles Bibliográficos
Autores principales: Tozzi, Marco, Larsen, Anna T., Lange, Sofie C., Giannuzzo, Andrea, Andersen, Martin N., Novak, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997690/
https://www.ncbi.nlm.nih.gov/pubmed/29895988
http://dx.doi.org/10.1038/s41598-018-27281-9

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