Cargando…

Deciphering Clinicoradiologic Phenotype for Thymidylate Synthase Expression Status in Patients with Advanced Lung Adenocarcinoma Using a Radiomics Approach

We aimed to identify predictive clinicoradiologic characteristics of thymidylate synthase (TS) expression status in advanced non-squamous non-small cell lung cancer patients. We reviewed clinicoradiologic features of 169 patients stratified into TS-negative (n = 84) and TS-positive (n = 85) groups,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, So Won, Park, Hyunjin, Lee, Ho Yun, Sohn, Insuk, Lee, Seung-Hak, Kang, Jun, Sun, Jong-Mu, Ahn, Myung-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997691/ https://www.ncbi.nlm.nih.gov/pubmed/29895834 http://dx.doi.org/10.1038/s41598-018-27273-9

Ejemplares similares

Prediction of tumor doubling time of lung adenocarcinoma using radiomic margin characteristics
por: Yoon, Hyun Jung, et al.
Publicado: (2020)

Deciphering the tumor microenvironment through radiomics in non-small cell lung cancer: Correlation with immune profiles
por: Yoon, Hyun Jung, et al.
Publicado: (2020)

Prognostic Impact of Longitudinal Monitoring of Radiomic Features in Patients with Advanced Non-Small Cell Lung Cancer
por: Bak, So Hyeon, et al.
Publicado: (2019)

Tumor Margin Contains Prognostic Information: Radiomic Margin Characteristics Analysis in Lung Adenocarcinoma Patients
por: Lee, Geewon, et al.
Publicado: (2021)

Computed Tomography Radiomics for Residual Positron Emission Tomography-Computed Tomography Uptake in Lymph Nodes after Treatment
por: Kim, Chu Hyun, et al.
Publicado: (2020)

Predictive and Prognostic Value of (18)F-fluorodeoxyglucose Uptake Combined with Thymidylate Synthase Expression in Patients with Advanced Non-Small Cell Lung Cancer
por: Moon, Seung Hwan, et al.
Publicado: (2019)

Significance of thymidylate synthase expression for resistance to pemetrexed in pulmonary adenocarcinoma
por: YANG, MIN, et al.
Publicado: (2014)

Parallel comparison and combining effect of radiomic and emerging genomic data for prognostic stratification of non‐small cell lung carcinoma patients
por: Kim, Ki Hwan, et al.
Publicado: (2020)

Effect of Hammerhead Ribozyme against Human Thymidylate Synthase on the Cytotoxicity of Thymidylate Synthase Inhibitors
por: Kobayashi, Hiroyuki, et al.
Publicado: (1995)

Decoding Tumor Phenotypes for ALK, ROS1, and RET Fusions in Lung Adenocarcinoma Using a Radiomics Approach
por: Yoon, Hyun Jung, et al.
Publicado: (2015)

Predictive value of thymidylate synthase for the prognosis and survival of lung adenocarcinoma patients
por: HUANG, YAN, et al.
Publicado: (2015)

Dynamic allostery in substrate binding by human thymidylate synthase
por: Bonin, Jeffrey P, et al.
Publicado: (2022)

Trichinella pseudospiralis vs. T. spiralis thymidylate synthase gene structure and T. pseudospiralis thymidylate synthase retrogene sequence
por: Jagielska, Elżbieta, et al.
Publicado: (2014)

Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells
por: Ciszewski, Wojciech M., et al.
Publicado: (2022)

Conservation and Role of Electrostatics in Thymidylate Synthase
por: Garg, Divita, et al.
Publicado: (2015)

3′-UTR Polymorphisms in Thymidylate Synthase with Colorectal Cancer Prevalence and Prognosis
por: Jeon, Young-Joo, et al.
Publicado: (2021)

Spread through air spaces (STAS) in invasive mucinous adenocarcinoma of the lung: Incidence, prognostic impact, and prediction based on clinicoradiologic factors
por: Lee, Min A., et al.
Publicado: (2020)

Reproducibility of radiomics for deciphering tumor phenotype with imaging
por: Zhao, Binsheng, et al.
Publicado: (2016)

Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in Plasmodium vivax field isolates that failed chloroquine treatment
por: Lee, Won-Ja, et al.
Publicado: (2010)

Substrate Activation in Flavin-Dependent Thymidylate Synthase
por: Mishanina, Tatiana V., et al.
Publicado: (2014)

Concerted versus Stepwise Mechanism in Thymidylate Synthase
por: Islam, Zahidul, et al.
Publicado: (2014)

Classification of the glioma grading using radiomics analysis
por: Cho, Hwan-ho, et al.
Publicado: (2018)

Radiomics in Breast Imaging from Techniques to Clinical Applications: A Review
por: Lee, Seung-Hak, et al.
Publicado: (2020)

Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC
por: Lee, Jae-Seon, et al.
Publicado: (2016)

Are radiomics features universally applicable to different organs?
por: Lee, Seung-Hak, et al.
Publicado: (2021)

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
por: Vijayakurup, Vinod, et al.
Publicado: (2022)

Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer
por: Ahn, Ji-Young, et al.
Publicado: (2015)

Expression of thymidylate synthase and orotate phosphoribosyltransferase in thymic carcinoma
por: YOKOTA, KEISUKE, et al.
Publicado: (2012)

Analysis of mRNA recognition by human thymidylate synthase
por: Brunn, Nicholas D., et al.
Publicado: (2014)

Bacterial versus human thymidylate synthase: Kinetics and functionality
por: Islam, Zahidul, et al.
Publicado: (2018)

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer
por: Siddiqui, Mohammad Aarif, et al.
Publicado: (2020)

Development and validation a radiomics nomogram for predicting thymidylate synthase status in hepatocellular carcinoma based on Gd-DTPA contrast enhanced MRI
por: Ding, Zongren, et al.
Publicado: (2023)

Pathologic stratification of operable lung adenocarcinoma using radiomics features extracted from dual energy CT images
por: Bae, Jung Min, et al.
Publicado: (2016)

Older adult-onset Alexander disease with atypical clinicoradiological features: a case report
por: Kang, You-Ri, et al.
Publicado: (2023)

Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase
por: Lee, Andrew L., et al.
Publicado: (2018)

An Evolutionary Analysis of Lateral Gene Transfer in Thymidylate Synthase Enzymes
por: Stern, Adi, et al.
Publicado: (2010)

Translational repression of thymidylate synthase by targeting its mRNA
por: Garg, Divita, et al.
Publicado: (2013)

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX
por: Basta, Tamara, et al.
Publicado: (2012)

Thymidylate Synthase as a Predictive Biomarker for Pemetrexed Response in NSCLC
por: Bukhari, Ali A., et al.
Publicado: (2013)

Flavin-Dependent Thymidylate Synthase as a New Antibiotic Target
por: Choi, Michael, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dt0n6n971ei2l7ve3ihdo27ke5