Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease

Neuronal loss alongside altered energy metabolism, are key features of Huntington’s disease (HD) pathology. The orexigenic gut-peptide hormone ghrelin is known to stimulate appetite and affect whole body energy metabolism. Liraglutide is an efficient anti-type 2 diabetes incretin drug, with neuropro...

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Detalles Bibliográficos
Autores principales: Duarte, Ana I., Sjögren, Marie, Santos, Maria S., Oliveira, Catarina R., Moreira, Paula I., Björkqvist, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997749/
https://www.ncbi.nlm.nih.gov/pubmed/29895889
http://dx.doi.org/10.1038/s41598-018-27121-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997749/
https://www.ncbi.nlm.nih.gov/pubmed/29895889
http://dx.doi.org/10.1038/s41598-018-27121-w

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