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A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile

Antibiotics are considered to be the first line of treatment for mild to moderately severe Clostridium difficile infection (CDI) in humans. However, antibiotics are also risk factors for CDI as they decrease colonization resistance against C. difficile by altering the gut microbiota and metabolome....

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Detalles Bibliográficos
Autores principales:	Thanissery, Rajani, Zeng, Daina, Doyle, Raul G., Theriot, Casey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997789/ https://www.ncbi.nlm.nih.gov/pubmed/29928268 http://dx.doi.org/10.3389/fmicb.2018.01206

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