Cytotoxic, DNA Cleavage and Pharmacokinetic Parameter Study of Substituted Novel Furan C-2 Quinoline Coupled 1, 2, 4-Triazole and Its Analogs

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BACKGROUND: Furan, quinoline and triazoles are known for their wide spectrum biologically active molecules. A series of novel furan C-2 quinoline and 1, 2, 4-triazole (FQT) coupled hybrids were designed and synthesized to evaluate for their DNA cleavage and cytotoxic studies. OBJECTIVES: In this wor...

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Detalles Bibliográficos
Autores principales: Anantacharya, Rajpurohit, Satyanarayan, Nayak D., Kalal, Bhuvanesh Sukhlal, Pai, Vinitha Ramanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2018
Materias:
Medicinal Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997846/
https://www.ncbi.nlm.nih.gov/pubmed/30008962
http://dx.doi.org/10.2174/1874104501812010060
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