Cargando…

The Severe Deficiency of the Somatotrope GH-Releasing Hormone/Growth Hormone/Insulin-Like Growth Factor 1 Axis of Ghrh(−/−) Mice Is Associated With an Important Splenic Atrophy and Relative B Lymphopenia

A debate is still open about the precise control exerted by the somatotrope GH-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor 1 axis on the immune system. The objective of this study was to directly address this question through the use of Ghrh(−/−) mice that exhibit a sever...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bodart, Gwennaelle, Farhat, Khalil, Renard-Charlet, Chantal, Becker, Guillaume, Plenevaux, Alain, Salvatori, Roberto, Geenen, Vincent, Martens, Henri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997896/ https://www.ncbi.nlm.nih.gov/pubmed/29928261 http://dx.doi.org/10.3389/fendo.2018.00296

Ejemplares similares

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae
por: Farhat, Khalil, et al.
Publicado: (2018)

SUN-117 Growth Hormone-Releasing Hormone (GHRH) Deficiency Promotes Inflammation Associated Carcinogenesis
por: Recinella, PharmD, Lucia, et al.
Publicado: (2020)

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of human malignant pleural mesothelioma
por: Villanova, Tania, et al.
Publicado: (2019)

Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity
por: Geenen, Vincent, et al.
Publicado: (2013)

SAT-603 Growth Hormone-Releasing Hormone (GHRH) Antagonists Stimulate Feeding in Mice
por: Leone, Sheila, et al.
Publicado: (2020)

Thyrotropin-Releasing Hormone (TRH) and Somatostatin (SST), but not Growth Hormone-Releasing Hormone (GHRH) nor Ghrelin (GHRL), Regulate Expression and Release of Immune Growth Hormone (GH) from Chicken Bursal B-Lymphocyte Cultures
por: Pech-Pool, Santiago, et al.
Publicado: (2020)

Growth hormone-releasing hormone (GHRH) polymorphisms associated with carcass traits of meat in Korean cattle
por: Cheong, Hyun Sub, et al.
Publicado: (2006)

Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2017)

Impact of Growth Hormone (GH) Deficiency and GH Replacement upon Thymus Function in Adult Patients
por: Morrhaye, Gabriel, et al.
Publicado: (2009)

Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1
por: Cui, Tengjiao, et al.
Publicado: (2018)

Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH)
por: Ayhan-Sahin, Burcu, et al.
Publicado: (2022)

Metastatic Pancreatic Neuroendocrine Tumor that Progressed to Ectopic Adrenocorticotropic Hormone (ACTH) Syndrome with Growth Hormone-releasing Hormone (GHRH) Production
por: Tadokoro, Rie, et al.
Publicado: (2016)

Tumorigenic transformation of human prostatic epithelial cell line RWPE‐1 by growth hormone‐releasing hormone (GHRH)
por: Muñoz‐Moreno, Laura, et al.
Publicado: (2022)

Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway
por: Guo, Jian, et al.
Publicado: (2010)

Growth Hormone (GH) and Cardiovascular System
por: Caicedo, Diego, et al.
Publicado: (2018)

Growth hormone (GH)–releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus?
por: Hersch, Elizabeth C, et al.
Publicado: (2008)

Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes
por: Luque, Raul M., et al.
Publicado: (2011)

Combined sprint and resistance training abrogates age differences in somatotropic hormones
por: Sellami, Maha, et al.
Publicado: (2017)

SUN-930 A Case of Acromegaly Secondary to Ectopic Growth Hormone-Releasing Hormone (GHRH) Secretion from a Bronchial Neuroendocrine Tumour
por: Bahrami, Jasmine, et al.
Publicado: (2020)

Crosstalk between Growth and Osmoregulation of GHRH-SST-GH-IGF Axis in Triploid Rainbow Trout (Oncorhynchus mykiss)
por: Xiang, Kaiwen, et al.
Publicado: (2022)

Genetic determinants of growth hormone and GH-related phenotypes
por: Hallengren, Erik, et al.
Publicado: (2017)

Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice
por: Recinella, Lucia, et al.
Publicado: (2023)

Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation
por: Hu, Rui, et al.
Publicado: (2016)

Accuracy and Limitations of the Growth Hormone (GH) Releasing Hormone-Arginine Retesting in Young Adults With Childhood-Onset GH Deficiency
por: Patti, Giuseppa, et al.
Publicado: (2019)

Assessment of Thymic Output Dynamics After in utero Infection of Mice With Coxsackievirus B4
por: Halouani, Aymen, et al.
Publicado: (2020)

Growth Hormone (GH) and Thyroid Stimulating Hormone (TSH) Co-Secreting Pituitary Macroadenoma
por: Maliakal, Alvin, et al.
Publicado: (2021)

Isolation and Characterization of the Arapaima gigas Growth Hormone (ag-GH) cDNA and Three-Dimensional Modeling of This Hormone in Comparison with the Human Hormone (hGH)
por: Lima, Eliana Rosa, et al.
Publicado: (2023)

Effects of Growth Hormone (GH) Supplementation on Dermatoscopic Evolution of Pigmentary Lesions in Children with Growth Hormone Deficiency (GHD)
por: Panarese, Fabrizio, et al.
Publicado: (2022)

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways
por: Cui, Tengjiao, et al.
Publicado: (2016)

Growth Hormone (GH) Hypersecretion and GH Receptor Resistance in Streptozotocin Diabetic Mice in Response to a GH Secretagogue
por: Johansen, Peter B., et al.
Publicado: (2003)

MON-437 Enteroendocrine Connections in Congenital Isolated GH Deficiency Due to GHRH Receptor Gene Mutation
por: Oliveira-Santos, Alecia, et al.
Publicado: (2019)

Long-term Safety of Growth Hormone in Adults With Growth Hormone Deficiency: Overview of 15 809 GH-Treated Patients
por: Johannsson, Gudmundur, et al.
Publicado: (2022)

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment
por: Tanaka, Toshiaki, et al.
Publicado: (2006)

Natriuretic Peptide Expression and Function in GH3 Somatolactotropes and Feline Somatotrope Pituitary Tumours
por: Mirczuk, Samantha M., et al.
Publicado: (2021)

In Search of the Hyperglycemic Threshold Required to Induce Growth Hormone (GH) Suppression
por: Bugalho, Maria João, et al.
Publicado: (2023)

Diagnosis of growth hormone (GH) deficiency: comparison of pituitary stalk interruption syndrome and transient GH deficiency
por: Louvel, Murielle, et al.
Publicado: (2009)

Favorable Impacts of Growth Hormone (GH) Replacement Therapy on Atherogenic Risks in Japanese Children with GH Deficiency
por: Kohno, Hitoshi, et al.
Publicado: (2012)

Prevalence of growth hormone (GH) deficiency in previously GH‐treated young adults with Prader‐Willi syndrome
por: Donze, Stephany H., et al.
Publicado: (2019)

New insights of growth hormone (GH) actions from tissue-specific GH receptor knockouts in mice
por: List, Edward O., et al.
Publicado: (2019)

Mixed gangliocytoma-pituitary adenoma containing GH and GHRH co-secreting adenoma cells
por: Teramoto, Shinichiro, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n0jl1d17f4s67f24d91igk0buf