In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines

This article contains data on in vitro cytotoxicity activity of chloroform, methanolic and water extracts of leaf and heartwood of Caesalpinia sappan L. a medicinal plant against Breast cancer (MCF-7) and Lung cancer (A-549) cells. This data shows that Brazilin A, a natural bioactive compound in hea...

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Autores principales: Naik Bukke, Arunkumar, Nazneen Hadi, Fathima, Babu, K. Suresh, shankar, P. Chandramati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Agricultural and Biological Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997910/
https://www.ncbi.nlm.nih.gov/pubmed/29900385
http://dx.doi.org/10.1016/j.dib.2018.05.050
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author Naik Bukke, Arunkumar
Nazneen Hadi, Fathima
Babu, K. Suresh
shankar, P. Chandramati
author_facet Naik Bukke, Arunkumar
Nazneen Hadi, Fathima
Babu, K. Suresh
shankar, P. Chandramati
author_sort Naik Bukke, Arunkumar
collection PubMed
description This article contains data on in vitro cytotoxicity activity of chloroform, methanolic and water extracts of leaf and heartwood of Caesalpinia sappan L. a medicinal plant against Breast cancer (MCF-7) and Lung cancer (A-549) cells. This data shows that Brazilin A, a natural bioactive compound in heartwood of Caesalpinia sappan L.induced cell death in breast cancer (MCF-7) cells. The therapeutic property was further proved by docking the Brazilin A molecule against BCL-2 protein (an apoptotic inhibitor) using auto dock tools.
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spelling pubmed-59979102018-06-13 In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines Naik Bukke, Arunkumar Nazneen Hadi, Fathima Babu, K. Suresh shankar, P. Chandramati Data Brief Agricultural and Biological Science This article contains data on in vitro cytotoxicity activity of chloroform, methanolic and water extracts of leaf and heartwood of Caesalpinia sappan L. a medicinal plant against Breast cancer (MCF-7) and Lung cancer (A-549) cells. This data shows that Brazilin A, a natural bioactive compound in heartwood of Caesalpinia sappan L.induced cell death in breast cancer (MCF-7) cells. The therapeutic property was further proved by docking the Brazilin A molecule against BCL-2 protein (an apoptotic inhibitor) using auto dock tools. Elsevier 2018-05-21 /pmc/articles/PMC5997910/ /pubmed/29900385 http://dx.doi.org/10.1016/j.dib.2018.05.050 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Agricultural and Biological Science
Naik Bukke, Arunkumar
Nazneen Hadi, Fathima
Babu, K. Suresh
shankar, P. Chandramati
In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title_full In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title_fullStr In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title_full_unstemmed In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title_short In vitro studies data on anticancer activity of Caesalpinia sappan L. heartwood and leaf extracts on MCF7 and A549 cell lines
title_sort in vitro studies data on anticancer activity of caesalpinia sappan l. heartwood and leaf extracts on mcf7 and a549 cell lines
topic Agricultural and Biological Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997910/
https://www.ncbi.nlm.nih.gov/pubmed/29900385
http://dx.doi.org/10.1016/j.dib.2018.05.050
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