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Helicase promotes replication re-initiation from an RNA transcript
To ensure accurate DNA replication, a replisome must effectively overcome numerous obstacles on its DNA substrate. After encountering an obstacle, a progressing replisome often aborts DNA synthesis but continues to unwind. However, little is known about how DNA synthesis is resumed downstream of an...
Autores principales: | Sun, Bo, Singh, Anupam, Sultana, Shemaila, Inman, James T., Patel, Smita S., Wang, Michelle D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997990/ https://www.ncbi.nlm.nih.gov/pubmed/29899338 http://dx.doi.org/10.1038/s41467-018-04702-x |
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