Cargando…
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. We hypothesize that loss of ANGPTL4 function might improve glucose homeostasis and decrease risk of type 2 diabetes (T2D). We investig...
Ejemplares similares
-
The Geisinger MyCode Community Health Initiative: an electronic health record-linked biobank for Precision Medicine research
por: Carey, David J., et al.
Publicado: (2016) -
A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers
por: Ayers, Kristin L., et al.
Publicado: (2016) -
Long-Term Weight-Loss in Gastric Bypass Patients Carrying Melanocortin 4 Receptor Variants
por: Moore, Bryn S., et al.
Publicado: (2014) -
Genetic variants help define the role of the MC4R C-terminus in signaling and cell surface stability
por: Moore, Bryn S., et al.
Publicado: (2018) -
A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic, and phenomic data domains
por: Wood, G. Craig, et al.
Publicado: (2017)