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Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time

Understanding the functional characteristics of naturally acquired antibodies against P. falciparum merozoite antigens is crucial for determining the protective functions of antibodies. Affinity (measured as k(d)) of naturally acquired antibodies against two key targets of acquired immunity, EBA175...

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Detalles Bibliográficos
Autores principales: Tijani, Muyideen K., Reddy, Sreenivasulu B., Langer, Christine, Beeson, James G., Wahlgren, Mats, Nwuba, Roseangela I., Persson, Kristina E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998021/
https://www.ncbi.nlm.nih.gov/pubmed/29899351
http://dx.doi.org/10.1038/s41598-018-27361-w