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Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP

Serine racemase (SR) catalyses two reactions: the reversible racemisation of L-serine and the irreversible dehydration of L- and D-serine to pyruvate and ammonia. SRs are evolutionarily related to serine dehydratases (SDH) and degradative threonine deaminases (TdcB). Most SRs and TdcBs – but not SDH...

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Detalles Bibliográficos
Autores principales:	Canosa, Andrea V., Faggiano, Serena, Marchetti, Marialaura, Armao, Stefano, Bettati, Stefano, Bruno, Stefano, Percudani, Riccardo, Campanini, Barbara, Mozzarelli, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998037/ https://www.ncbi.nlm.nih.gov/pubmed/29899358 http://dx.doi.org/10.1038/s41598-018-27227-1

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