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The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity
Ion channels are well placed to transduce environmental cues into signals used by cells to generate a wide range of responses, but little is known about their role in the regulation of RNA metabolism. Here we show that the TRPV4 cation channel binds the DEAD-box RNA helicase DDX3X and regulates its...
Autores principales: | Doñate-Macián, P., Jungfleisch, J., Pérez-Vilaró, G., Rubio-Moscardo, F., Perálvarez-Marín, A., Diez, J., Valverde, M. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998047/ https://www.ncbi.nlm.nih.gov/pubmed/29899501 http://dx.doi.org/10.1038/s41467-018-04776-7 |
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