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A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling
Several studies have demonstrated the remarkable properties of microbiota and their metabolites in the pathogenesis of several inflammatory diseases. 10-Hydroxy-cis-12-octadecenoic acid (HYA), a bioactive metabolite generated by probiotic microorganisms during the process of fatty acid metabolism, h...
Autores principales: | Yamada, Miki, Takahashi, Naoki, Matsuda, Yumi, Sato, Keisuke, Yokoji, Mai, Sulijaya, Benso, Maekawa, Tomoki, Ushiki, Tatsuo, Mikami, Yoshikazu, Hayatsu, Manabu, Mizutani, Yusuke, Kishino, Shigenobu, Ogawa, Jun, Arita, Makoto, Tabeta, Koichi, Maeda, Takeyasu, Yamazaki, Kazuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998053/ https://www.ncbi.nlm.nih.gov/pubmed/29899364 http://dx.doi.org/10.1038/s41598-018-27408-y |
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