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Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury

Autophagy has been implicated as a major factor in the development of a number of diseases of skeletal muscle. However, its role in skeletal muscle homeostasis is still evolving. We examined skeletal muscle architecture in a mouse model, Atg16L1, where autophagy is attenuated but importantly still p...

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Detalles Bibliográficos
Autores principales: Paolini, Andrea, Omairi, Saleh, Mitchell, Robert, Vaughan, Danielle, Matsakas, Antonios, Vaiyapuri, Sakthivel, Ricketts, Thomas, Rubinsztein, David C., Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998118/
https://www.ncbi.nlm.nih.gov/pubmed/29899362
http://dx.doi.org/10.1038/s41598-018-27429-7