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Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury
Autophagy has been implicated as a major factor in the development of a number of diseases of skeletal muscle. However, its role in skeletal muscle homeostasis is still evolving. We examined skeletal muscle architecture in a mouse model, Atg16L1, where autophagy is attenuated but importantly still p...
Autores principales: | Paolini, Andrea, Omairi, Saleh, Mitchell, Robert, Vaughan, Danielle, Matsakas, Antonios, Vaiyapuri, Sakthivel, Ricketts, Thomas, Rubinsztein, David C., Patel, Ketan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998118/ https://www.ncbi.nlm.nih.gov/pubmed/29899362 http://dx.doi.org/10.1038/s41598-018-27429-7 |
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