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Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer

Having demonstrated that apolipoprotein A-I (apoA-I) mimetic peptides ameliorate cancer in mouse models, we sought to determine the mechanism for the anti-tumorigenic function of these peptides. CT-26 cells (colon cancer cells that implant and grow into tumors in the lungs) were injected into wild-t...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Arnab, Yang, Xinying, Mukherjee, Pallavi, Sulaiman, Dawoud, Fogelman, Hannah R., Grijalva, Victor, Dubinett, Steven, Wasler, Tonya C., Paul, Manash K., Salehi-Rad, Ramin, Mack, Julia J., Iruela-Arispe, M. Luisa, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998131/
https://www.ncbi.nlm.nih.gov/pubmed/29899427
http://dx.doi.org/10.1038/s41598-018-26755-0