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A Humanized Mouse Model Generated Using Surplus Neonatal Tissue

Here, we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus and umbilical cord blood hematopoietic stem cells (HSCs). Conventional humanized mouse models are made by engrafting human fetal thymus and HSCs into immunocompromised mice....

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Detalles Bibliográficos
Autores principales:	Brown, Matthew E., Zhou, Ying, McIntosh, Brian E., Norman, Ian G., Lou, Hannah E., Biermann, Mitch, Sullivan, Jeremy A., Kamp, Timothy J., Thomson, James A., Anagnostopoulos, Petros V., Burlingham, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998340/ https://www.ncbi.nlm.nih.gov/pubmed/29576539 http://dx.doi.org/10.1016/j.stemcr.2018.02.011

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