Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor

Background: Previous studies have suggested a causative role for agonists of the aromatic hydrocarbon receptor (AhR) in the etiology of breast cancer 1, early-onset (BRCA-1)–silenced breast tumors, for which prospects for treatment remain poor. Objectives: We investigated the regulation of BRCA1 by...

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Detalles Bibliográficos
Autores principales: Romagnolo, Donato F, Donovan, Micah G, Papoutsis, Andreas J, Doetschman, Tom C, Selmin, Ornella I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998349/
https://www.ncbi.nlm.nih.gov/pubmed/29955703
http://dx.doi.org/10.3945/cdn.117.000562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998349/
https://www.ncbi.nlm.nih.gov/pubmed/29955703
http://dx.doi.org/10.3945/cdn.117.000562

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