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Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor
Background: Previous studies have suggested a causative role for agonists of the aromatic hydrocarbon receptor (AhR) in the etiology of breast cancer 1, early-onset (BRCA-1)–silenced breast tumors, for which prospects for treatment remain poor. Objectives: We investigated the regulation of BRCA1 by...
Autores principales: | Romagnolo, Donato F, Donovan, Micah G, Papoutsis, Andreas J, Doetschman, Tom C, Selmin, Ornella I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998349/ https://www.ncbi.nlm.nih.gov/pubmed/29955703 http://dx.doi.org/10.3945/cdn.117.000562 |
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