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Conditioned medium from bone marrow-derived mesenchymal stem cells inhibits vascular calcification through blockade of the BMP2–Smad1/5/8 signaling pathway
BACKGROUND: Arterial calcification is associated with cardiovascular disease as a complication of advanced atherosclerosis and is a significant contributor to cardiovascular morbidity and mortality. Osteoblastic differentiation of vascular smooth muscle cells (VSMCs) plays an important role in arter...
Autores principales: | Wang, Shuangshuang, Hu, Siwang, Wang, Jian, Liu, Yahui, Zhao, Ruochi, Tong, Maoqing, Cui, Hanbin, Wu, Nan, Chen, Xiaomin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998505/ https://www.ncbi.nlm.nih.gov/pubmed/29895327 http://dx.doi.org/10.1186/s13287-018-0894-1 |
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