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Conditioned medium from bone marrow-derived mesenchymal stem cells inhibits vascular calcification through blockade of the BMP2–Smad1/5/8 signaling pathway

BACKGROUND: Arterial calcification is associated with cardiovascular disease as a complication of advanced atherosclerosis and is a significant contributor to cardiovascular morbidity and mortality. Osteoblastic differentiation of vascular smooth muscle cells (VSMCs) plays an important role in arter...

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Detalles Bibliográficos
Autores principales: Wang, Shuangshuang, Hu, Siwang, Wang, Jian, Liu, Yahui, Zhao, Ruochi, Tong, Maoqing, Cui, Hanbin, Wu, Nan, Chen, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998505/
https://www.ncbi.nlm.nih.gov/pubmed/29895327
http://dx.doi.org/10.1186/s13287-018-0894-1

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