Hypoxia with Wharton’s jelly mesenchymal stem cell coculture maintains stemness of umbilical cord blood-derived CD34(+) cells

BACKGROUND: The physiological approach suggests that an environment associating mesenchymal stromal cells with low O(2) concentration would be most favorable for the maintenance of hematopoietic stem/progenitor cells (HSPCs). To test this hypothesis, we performed a coculture of cord blood CD34(+) ce...

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Detalles Bibliográficos
Autores principales: Zhao, Dewan, Liu, Lingjia, Chen, Qiang, Wang, Fangfang, Li, Qiuyang, Zeng, Qiang, Huang, Jingcao, Luo, Maowen, Li, Wenxian, Zheng, Yuhuan, Liu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998541/
https://www.ncbi.nlm.nih.gov/pubmed/29895317
http://dx.doi.org/10.1186/s13287-018-0902-5

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