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GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

BACKGROUND: Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behçet’s disease (BD). The objective of the present study was to clarify the pathological roles of CCR1 and IL10 loci identified by previous BD genome-wide association studies (GWASs). METHO...

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Detalles Bibliográficos
Autores principales:	Nakano, Hiroto, Kirino, Yohei, Takeno, Mitsuhiro, Higashitani, Kana, Nagai, Hideto, Yoshimi, Ryusuke, Yamaguchi, Yukie, Kato, Ikuma, Aoki, Ichiro, Nakajima, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998575/ https://www.ncbi.nlm.nih.gov/pubmed/29895319 http://dx.doi.org/10.1186/s13075-018-1613-0

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