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Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a

BACKGROUND: Long noncoding RNA HULC is highly up-regulation in human hepatocellular carcinoma (HCC). However, the functions of HULC in hepatocarcinogenesis remains unclear. METHODS: RT-PCR, Western blotting, Chromatin immunoprecipitation (CHIP) assay, RNA Immunoprecipitation (RIP) and tumorignesis t...

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Detalles Bibliográficos
Autores principales: Xin, Xiaoru, Wu, Mengying, Meng, Qiuyu, Wang, Chen, Lu, Yanan, Yang, Yuxin, Li, Xiaonan, Zheng, Qidi, Pu, Hu, Gui, Xin, Li, Tianming, Li, Jiao, Jia, Song, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998602/
https://www.ncbi.nlm.nih.gov/pubmed/29895332
http://dx.doi.org/10.1186/s12943-018-0843-8