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Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a
BACKGROUND: Long noncoding RNA HULC is highly up-regulation in human hepatocellular carcinoma (HCC). However, the functions of HULC in hepatocarcinogenesis remains unclear. METHODS: RT-PCR, Western blotting, Chromatin immunoprecipitation (CHIP) assay, RNA Immunoprecipitation (RIP) and tumorignesis t...
Autores principales: | Xin, Xiaoru, Wu, Mengying, Meng, Qiuyu, Wang, Chen, Lu, Yanan, Yang, Yuxin, Li, Xiaonan, Zheng, Qidi, Pu, Hu, Gui, Xin, Li, Tianming, Li, Jiao, Jia, Song, Lu, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998602/ https://www.ncbi.nlm.nih.gov/pubmed/29895332 http://dx.doi.org/10.1186/s12943-018-0843-8 |
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