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Lab on a Chip: Conquer Disease at the Earliest
Oral cancer is the fifth most common cancer in the world, accounting for numerous deaths annually. The 5-year survival rate remains approximately 50% for oral squamous cell carcinoma (OSCC) in the past several decades. Early detection plays a vital role in the survival rate of the patients. There is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998700/ https://www.ncbi.nlm.nih.gov/pubmed/29962801 http://dx.doi.org/10.4103/JPBS.JPBS_210_17 |
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author | Daniel, Gibson S. T. Thiruppathy, Manigandan Aswath, Nalini Narayanan, Sankar R. |
author_facet | Daniel, Gibson S. T. Thiruppathy, Manigandan Aswath, Nalini Narayanan, Sankar R. |
author_sort | Daniel, Gibson S. T. |
collection | PubMed |
description | Oral cancer is the fifth most common cancer in the world, accounting for numerous deaths annually. The 5-year survival rate remains approximately 50% for oral squamous cell carcinoma (OSCC) in the past several decades. Early detection plays a vital role in the survival rate of the patients. There is no accurate, cost-effective, and reliable method for the screening of patients with OSCC. Hence, many patients are diagnosed at advanced stages. Early detection would, therefore, help to identify patients and modify treatment with close monitoring. Lab on a Chip or micro-total-analysis systems are one of the microfluidics technologies that are defined as adaptation, miniaturization, integration, and automation of analytical laboratory procedures into a single device or “chip.” This technology assures the replacement of complicated techniques with miniaturized, integrated, programmed, and economical diagnostic devices. Hence, this system provides a means for rapid, automated, molecular analysis of cancer cells. |
format | Online Article Text |
id | pubmed-5998700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59987002018-06-29 Lab on a Chip: Conquer Disease at the Earliest Daniel, Gibson S. T. Thiruppathy, Manigandan Aswath, Nalini Narayanan, Sankar R. J Pharm Bioallied Sci Short Communication Oral cancer is the fifth most common cancer in the world, accounting for numerous deaths annually. The 5-year survival rate remains approximately 50% for oral squamous cell carcinoma (OSCC) in the past several decades. Early detection plays a vital role in the survival rate of the patients. There is no accurate, cost-effective, and reliable method for the screening of patients with OSCC. Hence, many patients are diagnosed at advanced stages. Early detection would, therefore, help to identify patients and modify treatment with close monitoring. Lab on a Chip or micro-total-analysis systems are one of the microfluidics technologies that are defined as adaptation, miniaturization, integration, and automation of analytical laboratory procedures into a single device or “chip.” This technology assures the replacement of complicated techniques with miniaturized, integrated, programmed, and economical diagnostic devices. Hence, this system provides a means for rapid, automated, molecular analysis of cancer cells. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5998700/ /pubmed/29962801 http://dx.doi.org/10.4103/JPBS.JPBS_210_17 Text en Copyright: © 2018 Journal of Pharmacy And Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Daniel, Gibson S. T. Thiruppathy, Manigandan Aswath, Nalini Narayanan, Sankar R. Lab on a Chip: Conquer Disease at the Earliest |
title | Lab on a Chip: Conquer Disease at the Earliest |
title_full | Lab on a Chip: Conquer Disease at the Earliest |
title_fullStr | Lab on a Chip: Conquer Disease at the Earliest |
title_full_unstemmed | Lab on a Chip: Conquer Disease at the Earliest |
title_short | Lab on a Chip: Conquer Disease at the Earliest |
title_sort | lab on a chip: conquer disease at the earliest |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998700/ https://www.ncbi.nlm.nih.gov/pubmed/29962801 http://dx.doi.org/10.4103/JPBS.JPBS_210_17 |
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