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Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study

Objectives: Low hydration has a deleterious effect on many conditions. In the absence of a urine concentrating defect, urine concentration is a marker of hydration status. However, markers to evaluate hydration status have not been well studied in children. The objectives of this paper are to compar...

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Autores principales: Walawender, Laura, Patterson, Jeremy, Strouse, Robert, Ketz, John, Saxena, Vijay, Alexy, Emily, Schwaderer, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998741/
https://www.ncbi.nlm.nih.gov/pubmed/29928640
http://dx.doi.org/10.3389/fped.2018.00160
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author Walawender, Laura
Patterson, Jeremy
Strouse, Robert
Ketz, John
Saxena, Vijay
Alexy, Emily
Schwaderer, Andrew
author_facet Walawender, Laura
Patterson, Jeremy
Strouse, Robert
Ketz, John
Saxena, Vijay
Alexy, Emily
Schwaderer, Andrew
author_sort Walawender, Laura
collection PubMed
description Objectives: Low hydration has a deleterious effect on many conditions. In the absence of a urine concentrating defect, urine concentration is a marker of hydration status. However, markers to evaluate hydration status have not been well studied in children. The objectives of this paper are to compare measures of thirst and urine concentration in children and to develop a novel mobile technology application to measure urine concentration. Study Design: Children age 12–17 years were selected (n = 21) for this pilot study. Thirst perception, specific gravity (automated dipstick analysis and refractometer), and urine color scale results were correlated to urine osmolality. The technology department developed a mobile technology camera application to measure light penetrance into urine which was tested on 25 random anonymized urine samples. Results: The patients' thirst perception and color scale as well as two researchers color scale did not significantly correlate with osmolality. Correlation between osmolality and hydration markers resulted in the following Pearson coefficients: SG automated dipstick, 0.61 (P 0.003); SG refractometer, 0.98 (P < 0.0001); urine color scale (patient), 0.37 (P 0.10), and light penetrance, −0.77 (P < 0.0001). The correlation of light penetrance with osmolality was stronger than all measures except SG by refractometer and osmolality. Conclusion: The mobile technology application may be a more accurate tool for urine concentration measurement than specific gravity by automated dipstick, subjective thirst, and urine color scale, but lags behind specific gravity measured by refractometer. The mobile technology application is a step toward patient oriented hydration strategies.
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spelling pubmed-59987412018-06-20 Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study Walawender, Laura Patterson, Jeremy Strouse, Robert Ketz, John Saxena, Vijay Alexy, Emily Schwaderer, Andrew Front Pediatr Pediatrics Objectives: Low hydration has a deleterious effect on many conditions. In the absence of a urine concentrating defect, urine concentration is a marker of hydration status. However, markers to evaluate hydration status have not been well studied in children. The objectives of this paper are to compare measures of thirst and urine concentration in children and to develop a novel mobile technology application to measure urine concentration. Study Design: Children age 12–17 years were selected (n = 21) for this pilot study. Thirst perception, specific gravity (automated dipstick analysis and refractometer), and urine color scale results were correlated to urine osmolality. The technology department developed a mobile technology camera application to measure light penetrance into urine which was tested on 25 random anonymized urine samples. Results: The patients' thirst perception and color scale as well as two researchers color scale did not significantly correlate with osmolality. Correlation between osmolality and hydration markers resulted in the following Pearson coefficients: SG automated dipstick, 0.61 (P 0.003); SG refractometer, 0.98 (P < 0.0001); urine color scale (patient), 0.37 (P 0.10), and light penetrance, −0.77 (P < 0.0001). The correlation of light penetrance with osmolality was stronger than all measures except SG by refractometer and osmolality. Conclusion: The mobile technology application may be a more accurate tool for urine concentration measurement than specific gravity by automated dipstick, subjective thirst, and urine color scale, but lags behind specific gravity measured by refractometer. The mobile technology application is a step toward patient oriented hydration strategies. Frontiers Media S.A. 2018-06-06 /pmc/articles/PMC5998741/ /pubmed/29928640 http://dx.doi.org/10.3389/fped.2018.00160 Text en Copyright © 2018 Walawender, Patterson, Strouse, Ketz, Saxena, Alexy and Schwaderer. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Walawender, Laura
Patterson, Jeremy
Strouse, Robert
Ketz, John
Saxena, Vijay
Alexy, Emily
Schwaderer, Andrew
Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title_full Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title_fullStr Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title_full_unstemmed Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title_short Mobile Technology Application for Improved Urine Concentration Measurement Pilot Study
title_sort mobile technology application for improved urine concentration measurement pilot study
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998741/
https://www.ncbi.nlm.nih.gov/pubmed/29928640
http://dx.doi.org/10.3389/fped.2018.00160
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