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Identification of novel drug targets for diamond-blackfan anemia based on RPS19 gene mutation using protein-protein interaction network

BACKGROUND: Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. In order to explore the molecular mechanisms of wild and mutated samples from DBA patients were exposed to bioinformatics investigation. Biological network of differentially expressed genes...

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Detalles Bibliográficos
Autores principales: Khan, Abbas, Ali, Arif, Junaid, Muhammad, Liu, Chang, Kaushik, Aman Chandra, Cho, William C. S., Wei, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998885/
https://www.ncbi.nlm.nih.gov/pubmed/29745857
http://dx.doi.org/10.1186/s12918-018-0563-0