Modulation of the expression of genes related to the system of amyloid-beta metabolism in the brain as a novel mechanism of ceftriaxone neuroprotective properties

BACKGROUND: The dominant hypothesis about the pathogenesis of Alzheimer’s disease (AD) is the “amyloid cascade” concept and modulating the expression of proteins involved in the metabolism of amyloid-beta (Aβ) is proposed as an effective strategy for the prevention and therapy of AD. Recently, we fo...

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Detalles Bibliográficos
Autores principales: Tikhonova, Maria A., Amstislavskaya, Tamara G., Belichenko, Victor M., Fedoseeva, Larisa A., Kovalenko, Sergey P., Pisareva, Ekaterina E., Avdeeva, Alla S., Kolosova, Nataliya G., Belyaev, Nikolai D., Aftanas, Lyubomir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998892/
https://www.ncbi.nlm.nih.gov/pubmed/29745864
http://dx.doi.org/10.1186/s12868-018-0412-5

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