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Multi-target drug repositioning by bipartite block-wise sparse multi-task learning

BACKGROUND: Finding potential drug targets is a crucial step in drug discovery and development. Recently, resources such as the Library of Integrated Network-Based Cellular Signatures (LINCS) L1000 database provide gene expression profiles induced by various chemical and genetic perturbations and th...

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Detalles Bibliográficos
Autores principales:	Li, Limin, He, Xiao, Borgwardt, Karsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998894/ https://www.ncbi.nlm.nih.gov/pubmed/29745839 http://dx.doi.org/10.1186/s12918-018-0569-7

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