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Haplotype analysis of APOE intragenic SNPs

BACKGROUND: APOE ε4 allele is most common genetic risk factor for Alzheimer’s disease (AD) and cognitive decline. However, it remains poorly understood why only some carriers of APOE ε4 develop AD and how ethnic variabilities in APOE locus contribute to AD risk. Here, to address the role of APOE hap...

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Detalles Bibliográficos
Autores principales:	Babenko, Vladimir N., Afonnikov, Dmitry A., Ignatieva, Elena V., Klimov, Anton V., Gusev, Fedor E., Rogaev, Evgeny I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998902/ https://www.ncbi.nlm.nih.gov/pubmed/29745836 http://dx.doi.org/10.1186/s12868-018-0413-4

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