Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
Vibrio vulnificus causes human sickness throughout the world via the consumption of undercooked seafood or exposure to contaminated water. Previous attempts at phylogenetic analyses of V. vulnificus have proven unsuccessful, mainly due to the poorly understood impact of factors on its divergence. In...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999204/ https://www.ncbi.nlm.nih.gov/pubmed/29928297 http://dx.doi.org/10.1111/eva.12602 |
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author | Yu, Shoukai |
author_facet | Yu, Shoukai |
author_sort | Yu, Shoukai |
collection | PubMed |
description | Vibrio vulnificus causes human sickness throughout the world via the consumption of undercooked seafood or exposure to contaminated water. Previous attempts at phylogenetic analyses of V. vulnificus have proven unsuccessful, mainly due to the poorly understood impact of factors on its divergence. In this study, we used advanced statistical and phylogenetic methods to strengthen the classification of V. vulnificus. This updated classification included the impact of geographical and host factors. The results demonstrate the existence of hierarchies and multidimensional effects in the classification of V. vulnificus, from the molecular level using biotypes, to the distributional level using geographical location, to the adaptational level through host immune response. These findings have implications for the classification of bacteria, bacterial evolution, and public health. |
format | Online Article Text |
id | pubmed-5999204 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-59992042018-06-20 Uncovering the geographical and host impacts on the classification of Vibrio vulnificus Yu, Shoukai Evol Appl Original Articles Vibrio vulnificus causes human sickness throughout the world via the consumption of undercooked seafood or exposure to contaminated water. Previous attempts at phylogenetic analyses of V. vulnificus have proven unsuccessful, mainly due to the poorly understood impact of factors on its divergence. In this study, we used advanced statistical and phylogenetic methods to strengthen the classification of V. vulnificus. This updated classification included the impact of geographical and host factors. The results demonstrate the existence of hierarchies and multidimensional effects in the classification of V. vulnificus, from the molecular level using biotypes, to the distributional level using geographical location, to the adaptational level through host immune response. These findings have implications for the classification of bacteria, bacterial evolution, and public health. John Wiley and Sons Inc. 2018-02-20 /pmc/articles/PMC5999204/ /pubmed/29928297 http://dx.doi.org/10.1111/eva.12602 Text en © 2018 The Authors. Evolutionary Applications published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Yu, Shoukai Uncovering the geographical and host impacts on the classification of Vibrio vulnificus |
title | Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
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title_full | Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
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title_fullStr | Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
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title_full_unstemmed | Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
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title_short | Uncovering the geographical and host impacts on the classification of Vibrio vulnificus
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title_sort | uncovering the geographical and host impacts on the classification of vibrio vulnificus |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999204/ https://www.ncbi.nlm.nih.gov/pubmed/29928297 http://dx.doi.org/10.1111/eva.12602 |
work_keys_str_mv | AT yushoukai uncoveringthegeographicalandhostimpactsontheclassificationofvibriovulnificus |