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Expression and purification of the mammalian translocator protein for structural studies
The translocator protein (TSPO) is an 18 kDa polytopic membrane protein of the outer mitochondrial membrane, abundantly present in the steroid-synthesising cells. TSPO has been linked to a number of disorders, and it is recognised as a promising drug target with a range of potential medical applicat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999236/ https://www.ncbi.nlm.nih.gov/pubmed/29897975 http://dx.doi.org/10.1371/journal.pone.0198832 |