Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphology, and satellite cell content

BACKGROUND: Recent studies have highlighted the JAK/STAT signaling pathway in the regulation of muscle satellite cell behavior. Herein we report preclinical studies designed to characterize the effects of a novel JAK/STAT inhibitor on plantar flexor skeletal muscle function, morphology, and satellit...

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Detalles Bibliográficos
Autores principales: Sorensen, Jacob R., Fuqua, Jordan D., Deyhle, Michael R., Parmley, Jacob, Skousen, Caitlin, Hancock, Chad, Parcell, Allen C., Hyldahl, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999283/
https://www.ncbi.nlm.nih.gov/pubmed/29897957
http://dx.doi.org/10.1371/journal.pone.0198611

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