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The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life
Early life events are associated with the susceptibility to chronic diseases in adult life. Perturbations of endoplasmic reticulum (ER) homeostasis activate the unfolded protein response (UPR), which contributes to the development of metabolic alterations. Our aim was to evaluate liver UPR in an ani...
Autores principales: | Deodati, Annalisa, Argemí, Josepmaría, Germani, Daniela, Puglianiello, Antonella, Alisi, Anna, De Stefanis, Cristiano, Ferrero, Roberto, Nobili, Valerio, Aragón, Tomás, Cianfarani, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999290/ https://www.ncbi.nlm.nih.gov/pubmed/29897997 http://dx.doi.org/10.1371/journal.pone.0198490 |
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