Glaucocalyxin A exerts anticancer effect on osteosarcoma by inhibiting GLI1 nuclear translocation via regulating PI3K/Akt pathway

Osteosarcoma, the most common malignant bone tumor with recurring disease or lung metastases, has become one of the leading causes of death in humans. In the current study, we made an investigation on the anticancer effect of glaucocalyxin A, a bioactive ent-kauranoid diterpenoid isolated from Rabdo...

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Detalles Bibliográficos
Autores principales: Zhu, Jianwei, Sun, Yang, Lu, Ying, Jiang, Xiubo, Ma, Bo, Yu, Lisha, Zhang, Jie, Dong, Xiaochen, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999605/
https://www.ncbi.nlm.nih.gov/pubmed/29899333
http://dx.doi.org/10.1038/s41419-018-0684-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999605/
https://www.ncbi.nlm.nih.gov/pubmed/29899333
http://dx.doi.org/10.1038/s41419-018-0684-9

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