Cargando…
Glaucocalyxin A exerts anticancer effect on osteosarcoma by inhibiting GLI1 nuclear translocation via regulating PI3K/Akt pathway
Osteosarcoma, the most common malignant bone tumor with recurring disease or lung metastases, has become one of the leading causes of death in humans. In the current study, we made an investigation on the anticancer effect of glaucocalyxin A, a bioactive ent-kauranoid diterpenoid isolated from Rabdo...
Autores principales: | Zhu, Jianwei, Sun, Yang, Lu, Ying, Jiang, Xiubo, Ma, Bo, Yu, Lisha, Zhang, Jie, Dong, Xiaochen, Zhang, Qi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999605/ https://www.ncbi.nlm.nih.gov/pubmed/29899333 http://dx.doi.org/10.1038/s41419-018-0684-9 |
Ejemplares similares
-
Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway
por: Lu, Ying, et al.
Publicado: (2018) -
Dieckol exerts anticancer activity in human osteosarcoma (MG-63) cells through the inhibition of PI3K/AKT/mTOR signaling pathway
por: Zhang, Shouqiang, et al.
Publicado: (2021) -
Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells
por: Lin, Wenfeng, et al.
Publicado: (2018) -
Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway
por: Liu, Bing, et al.
Publicado: (2017) -
Digoxin exerts anticancer activity on human nonsmall cell lung cancer cells by blocking PI3K/Akt pathway
por: Wang, Yingying, et al.
Publicado: (2021)