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肺癌干细胞Wnt信号通路的研究进展
Being the most critical signaling molecule in the Wnt pathway, the Wnt/β-catenin signaling pathway plays an important role in the maintenance of the cell proliferation and clone formation of lung cancer stem cells. Since it is closely related to the WNT pathway, the proliferation of lung cancer stem...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
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中国肺癌杂志编辑部
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999629/ https://www.ncbi.nlm.nih.gov/pubmed/21859553 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.08.11 |
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collection | PubMed |
description | Being the most critical signaling molecule in the Wnt pathway, the Wnt/β-catenin signaling pathway plays an important role in the maintenance of the cell proliferation and clone formation of lung cancer stem cells. Since it is closely related to the WNT pathway, the proliferation of lung cancer stem cells can be restrained by blocking the WNT pathway or influencing its key protein. Such method provides a new method for the treatment of lung cancer. By summarizing the state of-the-art research of lung cancer stem cells and the Wnt pathway from 2005 to 2010, their relationship is investigated. |
format | Online Article Text |
id | pubmed-5999629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | 中国肺癌杂志编辑部 |
record_format | MEDLINE/PubMed |
spelling | pubmed-59996292018-07-06 肺癌干细胞Wnt信号通路的研究进展 Zhongguo Fei Ai Za Zhi 综述 Being the most critical signaling molecule in the Wnt pathway, the Wnt/β-catenin signaling pathway plays an important role in the maintenance of the cell proliferation and clone formation of lung cancer stem cells. Since it is closely related to the WNT pathway, the proliferation of lung cancer stem cells can be restrained by blocking the WNT pathway or influencing its key protein. Such method provides a new method for the treatment of lung cancer. By summarizing the state of-the-art research of lung cancer stem cells and the Wnt pathway from 2005 to 2010, their relationship is investigated. 中国肺癌杂志编辑部 2011-08-20 /pmc/articles/PMC5999629/ /pubmed/21859553 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.08.11 Text en 版权所有©《中国肺癌杂志》编辑部2011 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | 综述 肺癌干细胞Wnt信号通路的研究进展 |
title | 肺癌干细胞Wnt信号通路的研究进展 |
title_full | 肺癌干细胞Wnt信号通路的研究进展 |
title_fullStr | 肺癌干细胞Wnt信号通路的研究进展 |
title_full_unstemmed | 肺癌干细胞Wnt信号通路的研究进展 |
title_short | 肺癌干细胞Wnt信号通路的研究进展 |
title_sort | 肺癌干细胞wnt信号通路的研究进展 |
topic | 综述 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999629/ https://www.ncbi.nlm.nih.gov/pubmed/21859553 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.08.11 |
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