BIM在非小细胞肺癌治疗中的作用及意义

B-cell lymphoma 2 interacting mediator of cell death (BIM) plays an important role in the progress of cell apoptosis. The lowering expression level or functional defect of which may have an negative effect on the efficacy of anticancer drugs and the prognosis of postoperative patients with non-small...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2016
Materias:
综述
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999635/
https://www.ncbi.nlm.nih.gov/pubmed/27866524
http://dx.doi.org/10.3779/j.issn.1009-3419.2016.11.12
Descripción
Sumario:B-cell lymphoma 2 interacting mediator of cell death (BIM) plays an important role in the progress of cell apoptosis. The lowering expression level or functional defect of which may have an negative effect on the efficacy of anticancer drugs and the prognosis of postoperative patients with non-small cell lung cancer (NSCLC). This review aims to summarize the structure and function of BIM, as well as the relationship between BIM and the therapeutic efficacy of NSCLC.

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