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岩藻糖基化与肿瘤
Fucosylation is one of the most important glycosylation in mamal, involving biosynthesis of blood H antigen and Lewis antigen, selectin mediated intravasion and homing of leukocyte, host-microbe interactions, modification of signaling. Alterations in the expression of fucosylated oligosaccharides ha...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999636/ https://www.ncbi.nlm.nih.gov/pubmed/27866519 http://dx.doi.org/10.3779/j.issn.1009-3419.2016.11.07 |
| _version_ | 1783331460622581760 |
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| collection | PubMed |
| description | Fucosylation is one of the most important glycosylation in mamal, involving biosynthesis of blood H antigen and Lewis antigen, selectin mediated intravasion and homing of leukocyte, host-microbe interactions, modification of signaling. Alterations in the expression of fucosylated oligosaccharides have been observed in several cancer, playing a role in proliferation, invasion, metastasis, immune escape and drug-sensitiity, especially in lung cancer. Targeting the abnormality of fucosylaion in cancer will become a new strategy. The role of fucosylation in cancer will be reviewed in this article. |
| format | Online Article Text |
| id | pubmed-5999636 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-59996362018-07-06 岩藻糖基化与肿瘤 Zhongguo Fei Ai Za Zhi 综述 Fucosylation is one of the most important glycosylation in mamal, involving biosynthesis of blood H antigen and Lewis antigen, selectin mediated intravasion and homing of leukocyte, host-microbe interactions, modification of signaling. Alterations in the expression of fucosylated oligosaccharides have been observed in several cancer, playing a role in proliferation, invasion, metastasis, immune escape and drug-sensitiity, especially in lung cancer. Targeting the abnormality of fucosylaion in cancer will become a new strategy. The role of fucosylation in cancer will be reviewed in this article. 中国肺癌杂志编辑部 2016-11-20 /pmc/articles/PMC5999636/ /pubmed/27866519 http://dx.doi.org/10.3779/j.issn.1009-3419.2016.11.07 Text en 版权所有©《中国肺癌杂志》编辑部2016 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
| spellingShingle | 综述 岩藻糖基化与肿瘤 |
| title | 岩藻糖基化与肿瘤 |
| title_full | 岩藻糖基化与肿瘤 |
| title_fullStr | 岩藻糖基化与肿瘤 |
| title_full_unstemmed | 岩藻糖基化与肿瘤 |
| title_short | 岩藻糖基化与肿瘤 |
| title_sort | 岩藻糖基化与肿瘤 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999636/ https://www.ncbi.nlm.nih.gov/pubmed/27866519 http://dx.doi.org/10.3779/j.issn.1009-3419.2016.11.07 |