体外循环在局部晚期肺恶性肿瘤切除手术中的应用体会

BACKGROUND AND OBJECTIVE: Cardiopulmonary bypass (CPB) in the treatment of locally advanced pulmonary malignant tumors invaded heart or great vessels was not well underwent. The aim of this study is to report the results of these cases with locally advanced pulmonary malignant tumor which were completely resected under CPB in our hospital. METHODS: Four patients with locally advanced pulmonary malignant tumors were operated under CPB. All patients had stage Ⅲb disease (T4N0M0). Moderate hypothermia CPB was used for all 4 cases. The CPB time was 79 min-155 min and aortic cross-clamp time was 57 min-126 min, respectively. RESULTS: There was no operative death in this series. CPB was smooth, and heart automatically rebeated in the 4 patients. All the 4 patients were discharged in 3 weeks. One patient dead of heart failure at 13 months after operation, one case dead of distant tumor metastasis at 22 months after operation. The other two patients have survived over 25 months and 11 months, respectively. CONCLUSION: CPB is helpful for completely removal of locally advanced pulmonary malignant tumors.