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Rotenone Treatment Reveals a Role for Electron Transport Complex I in the Subcellular Localization of Key Transcriptional Regulators During T Helper Cell Differentiation
Recent advances in our understanding of tumor cell mitochondrial metabolism suggest it may be an attractive therapeutic target. Mitochondria are central hubs of metabolism that provide energy during the differentiation and maintenance of immune cell phenotypes. Mitochondrial membranes harbor several...
Autores principales: | Ozay, Emrah Ilker, Sherman, Heather L., Mello, Victoria, Trombley, Grace, Lerman, Adam, Tew, Gregory N., Yadava, Nagendra, Minter, Lisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999735/ https://www.ncbi.nlm.nih.gov/pubmed/29930555 http://dx.doi.org/10.3389/fimmu.2018.01284 |
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