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PARP抑制剂对Lewis肺癌细胞及移植瘤放疗增敏作用及其机制
BACKGROUND AND OBJECTIVE: Te DNA damage of the irradiated tumor cells is mainly single strand breaks (SSBs) and double strand breaks (DSBs), in which the frequency of occurrence of SSBs is dozens of times than DSBs. However, most of the SSBs could be repaired by the Poly (ADP-Ribose) Polymerase (PAR...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999804/ https://www.ncbi.nlm.nih.gov/pubmed/26805733 http://dx.doi.org/10.3779/j.issn.1009-3419.2016.01.02 |