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非小细胞肺癌的BRAF基因突变及其临床意义
BRAF mutations have been found to be a driver mutation and maybe a therapy target in patients with non-small cell lung cancer. This article reviews the current understanding of BRAF gene, its structure, expression, the signal pathway, as well as its relationship with cancer especially the targeted t...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999868/ https://www.ncbi.nlm.nih.gov/pubmed/22429583 http://dx.doi.org/10.3779/j.issn.1009-3419.2012.03.09 |
| _version_ | 1783331536660070400 |
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| collection | PubMed |
| description | BRAF mutations have been found to be a driver mutation and maybe a therapy target in patients with non-small cell lung cancer. This article reviews the current understanding of BRAF gene, its structure, expression, the signal pathway, as well as its relationship with cancer especially the targeted therapies for non-small cell lung cancer. |
| format | Online Article Text |
| id | pubmed-5999868 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | 中国肺癌杂志编辑部 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-59998682018-07-06 非小细胞肺癌的BRAF基因突变及其临床意义 Zhongguo Fei Ai Za Zhi 综述 BRAF mutations have been found to be a driver mutation and maybe a therapy target in patients with non-small cell lung cancer. This article reviews the current understanding of BRAF gene, its structure, expression, the signal pathway, as well as its relationship with cancer especially the targeted therapies for non-small cell lung cancer. 中国肺癌杂志编辑部 2012-03-20 /pmc/articles/PMC5999868/ /pubmed/22429583 http://dx.doi.org/10.3779/j.issn.1009-3419.2012.03.09 Text en 版权所有©《中国肺癌杂志》编辑部2012 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
| spellingShingle | 综述 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title | 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title_full | 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title_fullStr | 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title_full_unstemmed | 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title_short | 非小细胞肺癌的BRAF基因突变及其临床意义 |
| title_sort | 非小细胞肺癌的braf基因突变及其临床意义 |
| topic | 综述 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999868/ https://www.ncbi.nlm.nih.gov/pubmed/22429583 http://dx.doi.org/10.3779/j.issn.1009-3419.2012.03.09 |
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