HPV和肺癌关系的研究进展

Lung cancer is one of malignant tumors harming human health. Over the past five decades, there is increasing morbidity and mortality of lung cancer which is the leading cause of cancer morbidity and mortality worldwide. Risk factors of lung cancer are versatile and smoking is among the important ones, but there are some non-smoking men, especially for women, some of whom developed lung cancer. Many studies showed that human papillomavirus (HPV) was the risk factor of lung cancer, however, which was less comprehensive or seriously estimated. The results of research on relationship between HPV infection and lung cancer are different because of the difference of detection methods, geographical distribution and sample size. Recently, the relationship of HPV and lung cancer is increasingly thought highly with deep study. Study advance of relationship between HPV and lung cancer in the recent years is briefly reviewed.